Resveratrol to help Diabetes and Obesity?

Another study…in a long line of them demonstrates the benefits from this incredible nutrient. This time it is an animal one which has shown this nutrient to be beneficial in helping avoid Diabetes and Obesity.

But…don’t rush out and buy Reservatrol just on the strength of this. It is only one of many nutrients that are needed for optimal health. Also, you don’t need to as we have a generous dose of it in our Total Balance. In fact, we were one of the first supplement companies to start using it years ago…. The 32mgs a day we use in Total Balance is the equivalent of what you would get in several bottles of red wine.

I will write in more detail about reservatrol later when my current work pressure eases a bit. I will tell you how Reservatrol has also been found to mimic calorie restriction which in turn leads to increased longevity…without having to starve yourself. Its pretty exciting stuff.

For the moment if you would like to know more about this latest study just read below for the article.

Resveratrol could counter metabolic diseases, animal study

Resveratrol, the phenolic derivative found in red wine and certain plants, may play a role in protecting against diabetes and obesity, suggest the results of an animal study.
Researchers from the University of Louis Pasteur, in collaboration with colleagues from Harvard and Kuopio Universities and Sirtis Pharmaceuticals, observed first that administering a dietary supplement of resveratrol to mice had an effect on the muscles of mice.

The muscle fibres used up a lot of oxygen and therefore had high energy expenditure during exercise, and they demonstrated a high level of endurance both during exercise and during in activity.

They went on to study the signaling pathway at a molecular level, in the mitochondrion organelle, which is responsible for energy production within the muscle cells. The resveratrol was seen to activate a protein in the Sirtuin family, which in turn stimulated the activity of another protein involved in mitochondrial function.

Thus, by enhancing energy expenditure, the researchers surmised that resveratrol led to a reduction in weight gain.

What is more, since the study found a link between sirtuins and energy expenditure, the researchers say there is a possibility that they may prove useful in the prevention or treatment of metabolic disorders - in particular certain pathologies related to mitochondrial dysfunction, as is often the case with obesity, type 2 diabetes and other ageing-related disorders.

The findings of the mice study are published in the peer reviewed journal Cell.

With view to substantiating the results in humans, Sirtris Pharmaceuticals has initiated a clinical trial on diabetes sufferers. However it is using a “confidential formulation of resveratrol, which has better bioavailability”.

Although this means that the outcome cannot necessarily be transposed to commercially available resveratrol in dietary supplements, this is the latest in a string of studies indicating that resveratrol packs a powerful health punch.

Last month Harvard researchers reported in Nature that resveratrol was seen to extended survival rates of mice and prevented the negative effects of high-calorie diets - findings described by an independent expert as potentially “the breakthrough of the year”.

Other recent research has linked resveratrol and red wine to a reduced risk of colorectal cancer and to slowing the progression of Alzheimer’s disease.

The ingredients industry has welcomed more research in this area. Moreover, Such studies are likely to have an accumulative effect on consumer awareness of resveratrol, whether gleaned from supplements or from natural food sources.

The amount of resveratrol in a bottle of red wine can vary between types of grapes and growing seasons, and can vary between 0.2 and 5.8 milligrams per litre. But nearly all dark red wines - merlot, cabernet, zinfandel, shiraz and pinot noir - contain resveratrol.

By the way, the reservatrol in Total Balance is as good as it gets for bio-availability due to the enteric coated delivery system we use.

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