D-Mannose is a simple sugar that occurs naturally in some plants, including cranberries. Although small amounts of D-Mannose are metabolized by the human body, much of it is rapidly excreted in the urine.
In the bladder, D-Mannose can adhere to bacterial lectins, preventing them from sticking to the lining of the bladder. Bacteria can then be flushed away during urination, thereby precluding the formation of colonies within the urinary tract. Because insubstantial amounts of D-Mannose are used by the body, it does not interfere with blood sugar regulation.
D-Mannose is a simple sugar that cures more than 90% of all urinary tract infections (most urinary tract infections are caused by E-Coli and D-Mannose is most effective on E-Coli) and, best of all, it does this without killing a single bacteria. Nearly 15 years of clinical experience has shown that D-Mannose is just as effective as antibiotics are at curing urinary tract infections. Seems to good to be true, right? An all natural simple sugar that’s completely safe, highly effective, inexpensive, and available without a prescription.
HOW IT WORKS
The answer is found in the interaction between D-Mannose and the bacterium found in over 90% of all bladder infections, Escherichia coli (”E. coli”). No, not the infamous E.coli mutants associated with unsanitary food processing that has hospitalized and killed people.
It’s the normal E.coli found as part of the “normal microflora” in every intestinal tract. But even normal E.coli do not belong in the bladder and urinary tract. In these areas they multiply and become an undesirable infection.
Why doesn’t the normal flow of urine from the kidneys through the urethras into the bladder and thence beyond simply carry the E.coli right along with it? What allows the E.coli to “stick” to the inner walls of the bladder and even work their way upward (like Spiderman) in some cases reaching as far as the kidneys?
The “cell walls” of each E.coli are covered with tiny fingerlike projections. The very tips of these projections are an amino acid-sugar complex, a “glycoprotein” also called a “lectin”. E.coli “lectins” have the unfortunate capability of enabling the bacteria to “stick” to the inside walls of our bladders and urinary tracts, so they can’t be rinsed out by urination.
Fortunately, D-Mannose “sticks” to E.coli lectins even better than E.coli lectin “sticks” to human cells. When we take a large quantity of D-Mannose, almost all of it spills into the urine through our kidneys, literally “coating” any E.coli present so they can no longer “stick” to the inside walls of the bladder and urinary tract. The E.coli are literally rinsed away with normal urination!
WHO CAN TAKE D-MANNOSE?
Who can’t? Because it is so effective and benign, even pregnant women who are susceptible to recurrent urinary tract infections can safely take D-Mannose as a preventative measure to ward off future attacks. D-Mannose is 100% safe for infants and young children and they will find the taste wonderful (it is sugar!).
And unlike antibiotics, one can safely stop treatment in a few days. An existing infection can be cleansed in as little as 1-3 days, after which you can stop taking D-Mannose if you wish. What about people who have diabetes? Diabetics usually need to limit their intake of sugar. If you have diabetes some people do report temporary increases in blood sugar levels, but the effect is not great and never permanent, lasting only for the length of time D-Mannose is used. D-mannose is very safe, even for long term use, although most women (or the very occasional man) with single episodes of bladder or urinary tract infection will only need it for a few days at most.
Although D-mannose is a simple sugar, very little of it is metabolized. It doesn�t interfere with blood sugar regulation, even for diabetics. It creates no disruption or imbalance in normal body microflora. In the less than 10% of cases where the infection is a bacteria other than E. coli, antibiotics can be started in plenty of time.
(Many physicians will likely advise collecting a urine specimen for culture, if possible just before starting D-mannose, so that the bacteria can be identified as rapidly as possible in the few cases where D-mannose doesn�t work.)
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